Risk-based management for the prevention of GBS infection in neonates
Introduction: Group B streptococcus (GBS) has been identified as one of the commonest causes of sepsis and meningitis in neonates leading to increased rates in neonatal morbidity and mortality among developed countries, while being correlated with resulting in preterm birth. At present, preventive antibiotic regimens are administered only to these pregnant women who have been identified as having risk factors to develop GBS infection or those with positive cultures for GBS, based on the updated guidelines (risk-based strategy). Methods: One of the goals of this research was to investigate if there is any correlation between GBS infection and preterm delivery, through looking thoroughly in the available GBS outcomes of the maternity unit that the study took place, as as well as to evaluate the effectiveness of current risk-based protocols compared to universal screening in the prevention of neonatal GBS disease. Results: GBS has been shown not to be an ...