Parenteral Diarrhea and Pediatric Urinary Tract Infections

 

Parenteral diarrhea is non-infectious diarrhea associated with extra intestinal infections such as otitis media, pneumonia, or urinary tract infection (UTI). This condition was first described in the late 19th century and has been discussed in recent reviews, there is limited understanding of the pathophysiology of non-infectious diarrhea associated with extraintestinal infection, and controversy exists about whether parenteral diarrhea is a distinct clinical condition.

In a retrospective cohort study of children presenting to a pediatric emergency department, non-infectious diarrhea was present in 18.6% of children who had culture-proven UTI.6 it is important to recognize the association between non-infectious diarrhea and urinary tract infections to avoid delayed diagnosis and treatment of associated urinary tract infections or misdiagnosis of infectious diarrhea. We hypothesized that an association exists between the presence of diarrhea and culture-proven UTI. The purpose of this systematic review of the literature was to determine the reported frequency of associated UTI in cohort and case control studies of pediatric patients who had diarrhea.



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