EFFECT OF PREGNANCY ON GLUCOSE LEVEL AND CARDIOVASCULAR PARAMETERS IN THE VARIOUS TRIMESTERS AND BABIES WEIGHT AT DELIVER

Pregnancy is associated with significant change in the functions of normal pancreas, Liver and the cardiovascular system. Although the precise mechanisms underlying these various alterations are not clear in every case, their recognition is essential for a proper clinical evaluation of their enhanced functions during pregnancy. This study was therefore undertaken to determine blood glucose level and cardiovascular parameters in the three trimesters of pregnancy among women in Benin City, Nigeria, since there have not been such studies in this part of the world. This was a prospective cohort study, in which fifty blood samples were collected at each mid trimester of pregnancy. Controls were age-matched non-pregnant women. Blood glucose was determined using glucose oxidase kit. Data was analyzed using ANOVA, and p≤ 0.05 was considered statistically significant. The results showed that glucose concentration was significantly higher in pregnant women than the control group, and it was highest in the third trimester of pregnancy. In conclusion, glucose production is increased from the onset of pregnancy to the last trimester.





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